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JoVE Journal Medicine
An Optimized Evans Blue Protocol to Assess Vascular Leak in the Mouse
 

An Optimized Evans Blue Protocol to Assess Vascular Leak in the Mouse

Article doi: 10.3791/57037
September 12th, 2018 •
1,2, 1,2, 1,2, 1,2,3
1Cardiovascular Pulmonary Research Laboratory, University of Colorado Denver, 2Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado Denver, 3Denver VA Medical Center

Summary
Automatic Translation
September 12th, 2018

In this article, an economical, optimized, and simple protocol is described which uses the Evans blue dye method for assessing plasma extravasation in the organs of FVBN mice that can be adapted for use in other strains, species, and other organs or tissues.

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