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A Mouse Model of Intestinal Partial Obstruction
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JoVE Journal Biology
A Mouse Model of Intestinal Partial Obstruction

A Mouse Model of Intestinal Partial Obstruction

DOI:
10.3791/57381-v

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07:33 min

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March 05, 2018

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, , , , , ,
1Department of Physiology and Cell Biology,University of Nevada, Reno School of Medicine, 2Department of Physiology, Wonkwang Digestive Disease Research Institute and Institute of Wonkwang Medical Science, School of Medicine,Wonkwang University

Chapters

  • 00:05Title
  • 00:59Partial Obstruction Surgery
  • 04:42Results: Representative Effects of Surgically-induced Intestinal Partial Obstruction
  • 06:25Conclusion

Summary

Automatic Translation

Automatic Translation

Intestinal obstructions are a partial or complete blockage of the intestine that can cause severe abdominal pain, nausea, vomiting, and preventing the passage of stool. This procedure for creating intestinal partial obsructions in mice is reliable in studying the mechanisms underlying pathological cell growth and death in the intestine.

Tags

Keywords: Intestinal Partial ObstructionMouse ModelCellular MechanismsIntestinal ObstructionPhenotypic ChangesSurgical ProcedureCecumIleumColonMesenterySilicone Ring

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