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Biology

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SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs
 

SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs

Article DOI: 10.3791/58133-v
June 28th, 2019

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Summary June 28th, 2019

Cellular senescence is the key factor in the development of chronic age-related pathologies. Identification of therapeutics that target senescent cells show promise for extending healthy aging. Here, we present a novel assay to screen for the identification of senotherapeutics based on measurement of senescence associated β-Galactosidase activity in single cells.

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