Journal
/
Chemistry
/
用于靶向质粒DNA输送的美聚氨酸功能化生物相容性块共聚物
JoVE Journal
Chemistry
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Chemistry
Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery
Please note that all translations are automatically generated. Click here for the English version.

用于靶向质粒DNA输送的美聚氨酸功能化生物相容性块共聚物

DOI:
10.3791/58527-v

•

08:09 min

•

August 06, 2019

•

, , , , , , ,
1Research Center of Clinical Oncology,Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & Nanjing Medical University Affiliated Cancer Hospital, 2Department of General Surgery,The First Affiliated Hospital with Nanjing Medical University, 3School of Clinical Medicine,Xuzhou Medical University

Chapters

  • 00:04Title
  • 01:09Synthesis of BNHEMA Polymer (PBNHEMA)
  • 03:21Synthesis of BNHEMA-b-APMA polymer (BA)
  • 04:18Transfection Efficiency of mBG/ GFP-pDNA Polyplexes
  • 05:10Results: Analysis of the Targeted Plasma DNA Delivery
  • 07:11Conclusion

Summary

Automatic Translation

Automatic Translation

本作品通过可逆添加-碎片链转移(RAFT)方法介绍了蛋氨酸功能化生物相容性块共聚物(mBG)的制备。研究了获得mBG的质粒DNA复合能力及其转染效率。RAFT方法对聚合含有特殊功能组的单体非常有益。

Tags

MethionineBlock CopolymerRAFT PolymerizationBiocompatiblePlasmid DNA Delivery

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

微波辅助分子内Diels-Alder反应的功能化萘/变色染料的合成脱氢

功能化的合成与表征金属 - 有机骨架

SDF-1α - 壳聚糖硫酸葡聚糖纳米粒子的制备与表征

单壁碳纳米管与热可逆嵌段共聚物及表征功能化小角度中子散射

从螺旋聚碳化二亚胺共聚物及其三唑衍生物获得自组装形貌

半导体回转金属硫框架结晶的硫醇构建块的合成

Preparation of Poly(pentafluorophenyl acrylate) Functionalized SiO2 Beads for Protein Purification

通过结晶驱动生物降解块共聚物的自组装合成单分散圆柱状纳米粒子

功能化单有机硼化合物共轭法高效合成全碳第四纪中心

18放射性跟踪器的F-标签，其功能与硅氟化物接受器（SiFA）进行正电子发射断层扫描

Read Article