A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Research Center of Clinical Oncology,Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & Nanjing Medical University Affiliated Cancer Hospital, 2Department of General Surgery,The First Affiliated Hospital with Nanjing Medical University, 3School of Clinical Medicine,Xuzhou Medical University
Chapters
- 00:04Title
- 01:09Synthesis of BNHEMA Polymer (PBNHEMA)
- 03:21Synthesis of BNHEMA-b-APMA polymer (BA)
- 04:18Transfection Efficiency of mBG/ GFP-pDNA Polyplexes
- 05:10Results: Analysis of the Targeted Plasma DNA Delivery
- 07:11Conclusion
Dette arbejde præsenterer forberedelsen af methionin funktionaliserede biokompatible blok copolymere (mBG) via den reversible tilsætning-fragmentering kæde overførsel (RAFT) metode. Plasmid-DNA-kompleksdannsevnen for den opnåede MBG og deres transfektering effektivitet blev også undersøgt. FLÅDEN metode er meget gavnlig for polymeriserende monomerer indeholder særlige funktionelle grupper.
