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Journal / Chemistry / Pretargeted Radioimmunotherapy 역 전자 수요 Diels 오리…
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Pretargeted Radioimmunotherapy 역 전자 수요 Diels 오리 나무 반응에 따라
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Pretargeted Radioimmunotherapy 역 전자 수요 Diels 오리 나무 반응에 따라

Article DOI: 10.3791/59041-v • 09:44 min • January 29th, 2019
January 29th, 2019 •
1,2, 1,2,3, 1,2,3,4
1Department of Chemistry, Hunter College of the City University of New York, 2Ph.D. Program in Chemistry, Graduate Center of the City University of New York, 3Department of Radiology, Memorial Sloan Kettering Cancer Center, 4Department of Radiology, Weill Cornell Medical College

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이 프로토콜 합성 및 트랜스-cyclooctene (TCO)의 특성에 설명 합니다-항 체와 177루 표시 tetrazine (Tz) radioligand pretargeted radioimmunotherapy (PRIT)에 대 한 수정. 또한, 그것은 자세히 biodistribution vivo에서 및 colorectal 암의 murine 모델에 경도 치료 연구에 대 한 이러한 두 가지 구조를 사용 하 여를 설명합니다.

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화학 문제점 143 radioimmunotherapy pretargeted radioimmunotherapy pretargeting 역 전자 수요 Diels 오리 나무 반응 tetrazine 트랜스-cyclooctene huA33 A33 항 루테튬-177
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