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基于逆电子需求函数-alder 反应的隐形放射免疫治疗

基于逆电子需求函数-alder 反应的隐形放射免疫治疗

Article doi: 10.3791/59041
January 29th, 2019

Summary January 29th, 2019

Please note that all translations are automatically generated.

Click here for the English version.

该协议描述了反式环磷 (tco) 修饰抗体和177个lu-tazine (tz) 辐射寡核苷酸的合成和表征, 用于预定目标放射治疗 (prit)。此外, 它还详细介绍了这两种结构在结直肠癌小鼠模型中的应用, 用于体内生物分布和纵向治疗研究。

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