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JoVE Journal
Cancer Research

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患者衍生的胰腺癌异质异种移植模型,使用斑马鱼幼虫作为比较药物评估的宿主
 
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患者衍生的胰腺癌异质异种移植模型,使用斑马鱼幼虫作为比较药物评估的宿主

Article DOI: 10.3791/59507-v
April 30th, 2019

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Summary April 30th, 2019

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该协议描述了基于病毒的双荧光标记肿瘤异种移植模型中的优化过程,使用幼虫斑马鱼作为宿主。这种异质异种异种移植模型模仿胰腺癌在体内微环境的组织组成,并作为在个性化zPDX(斑马鱼患者衍生异种移植)模型中评估药物反应的更精确的工具。

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