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JoVE Journal
Immunology and Infection

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Rescate del virus del Zika recombinante de un clon de ADNc cromosómico artificial bacteriano
 
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Rescate del virus del Zika recombinante de un clon de ADNc cromosómico artificial bacteriano

Article DOI: 10.3791/59537-v
June 24th, 2019

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Summary June 24th, 2019

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Click here for the English version.

La reciente epidemia del virus del Zika pone de relieve la importancia de establecer enfoques genéticos inversos para desarrollar vacunas y/o estrategias terapéuticas. Aquí, describimos el protocolo para rescatar un virus del Zika recombinante infeccioso de un clon de ADNc de longitud completa ensamblado en un cromosoma artificial bacteriano bajo el control del promotor inmediato-temprano del citomegalovirus humano.

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