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Neuroscience
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斑马鱼幼虫研究出血性脑卒中的病理后果
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal
Neuroscience
Using Zebrafish Larvae to Study the Pathological Consequences of Hemorrhagic Stroke
Please note that all translations are automatically generated.
Click here for the English version.
斑马鱼幼虫研究出血性脑卒中的病理后果
DOI:
10.3791/59716-v
•
06:36 min
•
June 05, 2019
•
Siobhan Crilly
,
Alexandra Njegic
,
Adrian R. Parry-Jones
3
,
Stuart M. Allan
3
,
Paul R. Kasher
3
1
Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Manchester Academic Health Science Centre
,
University of Manchester
,
2
Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre
,
University of Manchester
,
3
Lydia Becker Institute of Immunology and Inflammation
,
University of Manchester
Chapters
00:04
Title
00:35
Day 0: Egg Production and Collection
01:11
Day 1 – 2: Atorvastatin Treatment and ICH- and ICH+ Populations Separation
02:22
Day 3 – 5: Cell Death, Leukocyte Analysis and Motility Assay
04:24
Results: Intracerebral Hemorrhage (ICH) in Zebrafish Larvae
05:39
Conclusion
Summary
Automatic Translation
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Automatic Translation
在这里, 我们提出了一个程序来量化脑损伤, 运动缺陷和神经炎症出血后, 脑出血的斑马鱼幼虫, 在人的脑出血 (ICH) 的情况下。
Tags
Zebrafish Larvae
Hemorrhagic Stroke
Pre-clinical Approach
Cellular Response
Fluorescent Microscopy
Atorvastatin Treatment
Hemorrhaged Fish
Fluorescent Protein
Light Sheet Microscopy
Anesthetization
Low Melt Agarose
Mounting Capillary
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