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Traction mikroskopi integrert med materialer for chemotactic kollektiv migrasjon
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Traction mikroskopi integrert med materialer for chemotactic kollektiv migrasjon

Article DOI: 10.3791/60415-v • 10:53 min • October 13th, 2019
October 13th, 2019 •
1, 1, 2, 3, 3, 1
1Department of Biomedical Sciences, Korea University, 2Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, 3Department of Environmental Health, Harvard T.H. Chan School of Public Health

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Kollektive celle migrasjon i utvikling, sår helbredelse, og kreft metastasering er ofte guidet av graderinger av vekstfaktorer eller signalering molekyler. Beskrevet her er et eksperimentelt system som kombinerer trekkraft mikroskopi med et mikrovæskebasert system og en demonstrasjon av hvordan å kvantifisere mekanikken i kollektiv migrasjon under biokjemiske gradient.

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Bioteknologi materialer trekkraft mikroskopi kollektiv celle migrasjon chemotaxis kjemisk gradient micropatterning
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