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JoVE Journal Bioengineering
Design eines biokompatiblen trachealen Stents bei Mäusen mit Laryngotrachealstenose
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Design eines biokompatiblen trachealen Stents bei Mäusen mit Laryngotrachealstenose

Article DOI: 10.3791/60483-v • 08:26 min • January 21st, 2020
January 21st, 2020 •
1, 2, 2, 2, 2, 2, 2
1Department of General Surgery, University of California, San Francisco, 2Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine

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Laryngotrachealstenose resultiert aus pathologischer Narbenablagerung, die die Luftröhre kritisch verengt und keine wirksamen medizinischen Therapien hat. Mit einem PLLA-PCL (70% Poly-L-Laktid und 30% Polycaprolacton) Stent als lokales Arzneimittelabgabesystem, können mögliche Therapien zur Verringerung der Narbenproliferation in der Luftröhre untersucht werden.

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Bioengineering Ausgabe 155 drogenverdünnender Stent PLLA-PCL Rapamycin Laryngotrachealstenose Trachealstenose Fibrose
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