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JoVE Journal Bioengineering
Utformning av en biokompatibel drog-Eluting Trakealstent hos möss med Laryngotrakeal stenos
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Utformning av en biokompatibel drog-Eluting Trakealstent hos möss med Laryngotrakeal stenos

Article DOI: 10.3791/60483-v • 08:26 min • January 21st, 2020
January 21st, 2020 •
1, 2, 2, 2, 2, 2, 2
1Department of General Surgery, University of California, San Francisco, 2Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine

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Laryngotrakeal stenos resultat från patologiska ärr deposition som kritiskt smalnar trakealluftvägarna och saknar effektiva medicinska terapier. Med hjälp av en PLLA-PCL (70% Poly-L-lactide och 30% polycaprolactone) stent som ett lokalt läkemedel leveranssystem, potentiella terapier som syftar till att minska ärr spridning i luftstrupen kan studeras.

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Bioteknik utgåva 155 läkemedels-eluting stent PLLA-PCL rapamycin laryngotrakeal stenos trakealstenos fibros
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