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Perfusion and Inflation of the Mouse Lung for Tumor Histology
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Cancer Research
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JoVE Journal Cancer Research
Perfusion and Inflation of the Mouse Lung for Tumor Histology

Perfusion and Inflation of the Mouse Lung for Tumor Histology

DOI:
10.3791/60605-v

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04:24 min

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August 06, 2020

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, , ,
1Department of Genetics,University of Alabama at Birmingham, 2Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine,Vanderbilt University School of Medicine

Chapters

  • 00:04Introduction
  • 00:22Experimental Protocol
  • 03:23Results: Representative H&E Staining

Summary

Automatic Translation

Automatic Translation

The purpose of this method is to present a simple and efficient method for the perfusion, inflation, and fixation of mouse lungs for the examination of lung tumor pathology and evaluation of metastases to the lung.

Tags

Mouse LungTumor HistologyPerfusionInflationEuthanasiaAbdominal IncisionThoracic CavityDiaphragmTracheaRight VentricleHeparinFormalinLung Inflation

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