Journal
/
/
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
JoVE Journal
Bioengineering
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Bioengineering
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
DOI:

10:35 min

February 25, 2020

, , ,

Chapters

  • 00:05Introduction
  • 01:26Dermal Graft Preparation
  • 03:13Muscle Graft Preparation
  • 04:44Common Peroneal (CP) Nerve Isolation and Preparation
  • 06:26Composite Regenerative Peripheral Nerve Interface (C-RPNI) Construct Fabrication
  • 08:20Results: Representative C-RPNI Characterization and Functional Analysis
  • 09:46Conclusion

Summary

Automatic Translation

The following manuscript describes a novel method for developing a biologic, closed loop neural feedback system termed the composite regenerative peripheral nerve interface (C-RPNI). This construct has the ability to integrate with peripheral nerves to amplify efferent motor signals while simultaneously providing afferent sensory feedback.

Related Videos

Read Article