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Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans
 

Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans

Article DOI: 10.3791/61169-v
August 15th, 2020

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Summary August 15th, 2020

Here, we introduce and describe widely accessible methodologies utilizing some versatile nematode models, including hyperactivated ion channel-induced necrosis and protein aggregate-induced neurotoxicity, to monitor and dissect the cellular and molecular underpinnings of age-associated neurodegenerative diseases.

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