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Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
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Chapters
- 00:04Introduction
- 00:43Stereotactic Frame and Mouse Preparation
- 01:46Calvarial Window Generation
- 02:50Cancer Cell Injection
- 04:08Magnetic Resonance Imaging (MRI)
- 04:54Volumetric Tumor Measurement
- 05:28Results: Representative Tumor Burden Tracking and Volume Quantification
- 06:08Conclusion
Intracranial brain metastasis modeling is complicated by an inability to monitor tumor size and response to treatment with precise and timely methods. The presented methodology couples intracranial tumor injection with magnetic resonance imaging analysis, which when combined, cultivates precise and consistent injections, enhanced animal monitoring, and accurate tumor volume measurements.
