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Cancer Research

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Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis
 

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis

Article doi: 10.3791/55085
February 8th, 2017

Summary February 8th, 2017

Brain metastasis has become an urgent unmet medical need as its incidence has increased while therapeutic options have remained palliative. Creating experimental animal models of brain metastasis via intracarotid arterial injection of cancer cells facilitates mechanistic studies of the disease biology and evaluation of novel intervention regimens.

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