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Journal / Bioengineering / Afbødning af blodbårne celle vedhæftet fil til…
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Bioengineering

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JoVE Journal Bioengineering
Afbødning af blodbårne celle vedhæftet fil til metal implantater gennem CD47-Afledt peptid immobilisering
Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
Journal (Bioengineering)
Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
Development of a Multicellular Three-dimensional Organotypic Model of the Human Intestinal Mucosa Grown Under Microgravity
Journal (Bioengineering)
Development of a Multicellular Three-dimensional Organotypic Model of the Human Intestinal Mucosa Grown Under Microgravity
 
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Afbødning af blodbårne celle vedhæftet fil til metal implantater gennem CD47-Afledt peptid immobilisering

Article DOI: 10.3791/61545-v • 08:13 min • December 3rd, 2020
December 3rd, 2020 •
1, 1, 1,2, 1,2, *1,2, *1,2
1The Children's Hospital of Philadelphia, 2Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania
* These authors contributed equally

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Præsenteret her er en protokol for tilføjelse peptid CD47 (pepCD47) til metal stents ved hjælp af polybisfosfonat kemi. Funktionalisering af metal stents ved hjælp af pepCD47 forhindrer fastgørelse og aktivering af inflammatoriske celler og dermed forbedre deres biokompatibilitet.

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Bioengineering overfladefunktionalisering metal implantater stents CD47 inflammation trombose peptider biokonjugation
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