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An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices
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An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices

Article DOI: 10.3791/61570-v • 08:44 min • August 21st, 2020
August 21st, 2020 •
1, 2, 3, 1, 1, 1, 1, 4, 1, 1
1Department of Cardiothoracic Surgery, Otto-von-Guericke-University, 2Department of Mechanical Engineering, Institute for Materials and Joining Technology, Otto-von-Guericke-University, 3Institute of Clinical Chemistry and Pathobiochemistry, Otto-von-Guericke-University, 4Division of Cardiology and Angiology, Department of Internal Medicine, Otto-von-Guericke-University

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Summary
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Presented here is a protocol for a standardized in vitro hemodynamic loop model. This model allows to test the hemocompatibility of perfusion tubes or vascular stents to be in accordance with ISO (International Organization for Standardization) standard 10993-4.

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Hemodynamic Loop Model In Vitro Hemocompatibility Host Cell Activation Vascular Medical Devices Perfusion Tubing Stents Standardized Conditions Mechanical Part Assembly Loop Closure System Blood Loading Tube Cutter Inner Diameter Outer Diameter Loop Shape Locking Screw Tension Band Connector Polycarbonate Band Stent Loop Assembly
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