An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices

Max Wacker; Ulf Betke; Katrin Borucki; J&#246;rn H&#252;lsmann; George Awad; Sam Varghese; Maximilian Scherner; Michael Hansen; Jens Wippermann; Priya Veluswamy

doi:10.3791/61570

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Un modelo de bucle hemodinámico In Vitro para investigar la hemocitocompatibilidad y la activación de células host de dispositivos médicos vasculares

An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices

JoVE Journal
Medicine
Author Produced

This content is Free Access.

JoVE Journal Medicine

An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices

Un modelo de bucle hemodinámico In Vitro para investigar la hemocitocompatibilidad y la activación de células host de dispositivos médicos vasculares

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7,067 Views

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08:44 min

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August 21, 2020

DOI:

10.3791/61570-v

DOI:

10.3791/61570-v

•

08:44 min

August 21, 2020

•

7045 Views

Max Wacker¹, Ulf Betke², Katrin Borucki³, Jörn Hülsmann¹, George Awad¹, Sam Varghese¹, Maximilian Scherner¹, Michael Hansen⁴, Jens Wippermann¹, Priya Veluswamy¹

¹Department of Cardiothoracic Surgery,Otto-von-Guericke-University ²Department of Mechanical Engineering, Institute for Materials and Joining Technology,Otto-von-Guericke-University ³Institute of Clinical Chemistry and Pathobiochemistry,Otto-von-Guericke-University ⁴Division of Cardiology and Angiology, Department of Internal Medicine,Otto-von-Guericke-University

Summary

Aquí se presenta un protocolo para un modelo de bucle hemodinámico estandarizado. Este modelo permite probar la hemocompatibilidad de tubos de perfusión o stents vasculares para estar de acuerdo con la norma ISO (International Organization for Standardization) 10993-4.