A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Department of Dental Materials and Prosthodontics, School of Dentistry,São Paulo State University (UNESP), 2Department of Organic Chemistry, Institute of Chemistry,São Paulo State University (UNESP), 3Faculty of Pharmaceutical Sciences of Ribeiraão Preto (FCFRP-USP), Department of Physics and Chemistry,University of São Paulo
Chapters
- 00:04Introduction
- 00:53Preparation of Crude Extracts (CE) and Fractions (CEF) to Chemical Profile Analysis and Bioassays
- 02:26Bioassay and Anti-microbial Activity
- 04:10Validation of Biological Activity and Biological Data Analysis
- 06:16Results: The Screening Results of the Twelve Crude Extracts from Three Varieties of C. sylvestris Against S. mutans
- 07:31Conclusion
Os produtos naturais representam pontos de partida promissores para o desenvolvimento de novas drogas e agentes terapêuticos. No entanto, devido à alta diversidade química, encontrar novos compostos terapêuticos das plantas é uma tarefa desafiadora e demorada. Descrevemos uma abordagem simplificada para identificar moléculas antimicrobianas e antibiofilmes a partir de extratos e frações vegetais.
