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在 NAFLD/NASH 的鼠模型中应用超声波和剪切波弹性成像
JoVE Journal
Biology
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JoVE Journal
Biology
Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
Please note that all translations are automatically generated.
Click here for the English version.
在 NAFLD/NASH 的鼠模型中应用超声波和剪切波弹性成像
DOI:
10.3791/62403-v
•
07:13 min
•
April 20, 2021
•
Jeffrey Morin*
1
,
Terri A. Swanson*
2
,
Anthony Rinaldi
,
Magalie Boucher
,
Trenton Ross
,
Dinesh Hirenallur-Shanthappa
1
Comparative Medicine
,
Pfizer Inc.
,
2
Digital Medicine & Translational Imaging
,
Pfizer Inc.
,
3
Internal Medicine Research Unit
,
Pfizer Inc.
,
4
Drug Safety Research & Development
,
Pfizer Inc.
Chapters
00:05
Introduction
00:40
Preparation of Rat for Imaging and Instrument Set-up
02:01
Image Acquisition for Hepato-Renal (HR) Index Measurement
03:27
Image Acquisition for the Shear Wave Elastography
04:43
Image Data Retrieval
05:12
Results: Analysis of the Hepato-renal Index and Shear Wave Elastography in High-fat and Control Diet Groups
06:37
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
本协议描述了使用增强的超声波技术来无侵入性地观察和量化非酒精性脂肪肝病啮齿动物模型中的肝脏组织变化。
Tags
Ultrasound
Shear Wave Elastography
NAFLD
NASH
Rat Model
Non-invasive
High-throughput
Drug Discovery
Choline Deficient High-fat Diet
Anesthesia
Chemical Depilation
B-mode Imaging
Renal Cortex
Liver Parenchyma
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