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Journal
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Neuroscience
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烧伤诱导的疼痛和小鼠抑郁样行为
JoVE Journal
Neuroscience
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JoVE Journal
Neuroscience
Burn Injury-Induced Pain and Depression-Like Behavior in Mice
Please note that all translations are automatically generated.
Click here for the English version.
烧伤诱导的疼痛和小鼠抑郁样行为
DOI:
10.3791/62817-v
•
07:08 min
•
September 29, 2021
•
Jae-Gyun Choi*
1
,
Dong-Wook Kang*
1
,
Jaehyuk Kim
,
Miae Lee
,
Sheu-Ran Choi
,
Jin Bong Park
,
Hyun-Woo Kim
1
Department of Physiology and Medical Science, College of Medicine and Brain Research Institute
,
Chungnam National University
,
2
Department of Pharmacology
,
Catholic Kwandong University College of Medicine
Chapters
00:04
Introduction
00:44
Induction of Scalding Burn Injury on the Hind Paw
01:43
Measurement of Mechanical Allodynia and Automated Gait Analysis
03:49
Measurement of Depression-Like Behavior and Normal Motor Function
04:45
Results: Mechanical Allodynia, Gait Analysis, and Depression-Like Behavior in Burn Injury-Induced Mice
06:23
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
一个后爪的短暂性烫伤(65 °C ± 0.5 °C,3 s)降低了同侧冯弗雷丝刺激的阈值(g)并改变了步态模式。此外,烧伤在强制游泳测试中诱发抑郁样行为。
Tags
Burn Injury
Pain
Depression-like Behavior
Mouse Model
Mechanical Threshold
Gait Analysis
Von Frey Filaments
Hot Water-induced Burn
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