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Neuroscience

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Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice
 

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Article doi: 10.3791/57349
June 29th, 2018

Summary June 29th, 2018

We describe the use of optogenetics and electrophysiological recordings for selective manipulations of hippocampal theta oscillations (5-10 Hz) in behaving mice. The efficacy of the rhythm entrainment is monitored using local field potential. A combination of opto- and pharmacogenetic inhibition addresses the efferent readout of hippocampal synchronization.

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