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Omvendt genetisk tilgang til at identificere pigmentregulatorer ved hjælp af zebrafisk
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Omvendt genetisk tilgang til at identificere pigmentregulatorer ved hjælp af zebrafisk

Article DOI: 10.3791/62955-v • 07:16 min • March 1st, 2022
March 1st, 2022 •
*1,2, *1,2, 1,2,3, 1,2, 1, 1,2
1CSIR-Institute of Genomics and Integrative Biology, 2Academy of Scientific and Innovative Research, 3Division of Biology and Biological Engineering, California Institute of Technology
* These authors contributed equally

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Regulatorer af melanocytfunktioner styrer synlige forskelle i pigmenteringsresultatet. Dekryptering af den molekylære funktion af kandidatpigmenteringsgenet udgør en udfordring. Heri demonstrerer vi brugen af et zebrafiskmodelsystem til at identificere kandidater og klassificere dem i regulatorer af melaninindhold og melanocytantal.

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Biologi nr. 181
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