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Journal / Neuroscience / Transplantasjon av human indusert pluripotent…
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Neuroscience

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JoVE Journal Neuroscience
Transplantasjon av human indusert pluripotent stamcelle-avledet mikroglia i immunompetent mus hjerne via ikke-invasiv transnasal rute
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Transplantasjon av human indusert pluripotent stamcelle-avledet mikroglia i immunompetent mus hjerne via ikke-invasiv transnasal rute

Article DOI: 10.3791/63574-v • 05:35 min • May 31st, 2022
May 31st, 2022 •
1,2, 1,2, 1,2, 1,2
1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi

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Protokollen som presenteres her tillater transplantasjon av indusert pluripotent stamcelle-avledet menneskelig mikroglia (iPSMG) inn i hjernen via en transnasal rute i immunodumpente mus. Metoden for fremstilling og transnasal transplantasjon av celler og administrering av cytokinblanding for vedlikehold av iPSMG er vist.

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