Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Neuroscience

A subscription to JoVE is required to view this content.

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
 

Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods

Article DOI: 10.3791/64014-v 09:29 min August 4th, 2022
August 4th, 2022

Chapters

Summary

The combination of laser capture microdissection and microfluidic RT-qPCR provides anatomic and biotechnical specificity in measuring the transcriptome in single neurons and glia. Applying creative methods with a system's biology approach to psychiatric disease may lead to breakthroughs in understanding and treatment such as the neuroinflammation antireward hypothesis in addiction.

Tags

Single-cell Gene Expression Anatomically Specific High Throughput Spatial Specificity Molecular Specificity QPCR Chip Microfluidic Mixing Device Prime Script PCR Sample Plate Reaction Assay Well Microfluidic RT-qPCR Platform Data Collection Software
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter