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Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
JoVE Journal
Medicine
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JoVE Journal Medicine
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
DOI:

07:12 min

August 17, 2022

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Chapters

  • 00:05Introduction
  • 00:53Animal Preparation
  • 02:05Incision, Dissection of the Subcutaneous Tissue, and Anterior Neck Muscle Fixation
  • 02:56Thyroid Gland Localization and Visual Identification of the Parathyroid Gland (PGs)
  • 04:18Black Iron Oxide Nanoparticles (IONPs) Injection and PGs Identification
  • 05:09Results: Effects of IONP Injection and PGs Identification Post-Injection
  • 05:51Conclusion

Summary

Automatic Translation

To date, the development of parathyroid gland (PG) identification methods is limited by the lack of animal models in preclinical research. Here, we establish a simple and effective rat model for intraoperative PG imaging and evaluate its effectiveness by using iron oxide nanoparticles as a novel PG contrast agent.

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