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JoVE Journal Cancer Research
Ensaio de Triagem de Alto Conteúdo para Identificação de Compostos Modificadores de Citotoxicidade Celular Dependente de Anticorpos
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Ensaio de Triagem de Alto Conteúdo para Identificação de Compostos Modificadores de Citotoxicidade Celular Dependente de Anticorpos

Article DOI: 10.3791/64485-v • 13:59 min • August 18th, 2023
August 18th, 2023 •
*1,2, *1,3, *1,3, 1, 1,4, 1,4
1Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, 2Doctoral School of Molecular Medicine, University of Debrecen, 3National Academy of Scientist Education, University of Debrecen, 4ELKH-DE Cell Biology and Signaling Research Group
* These authors contributed equally

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Este protocolo apresenta uma técnica automatizada de alto rendimento baseada em imagem para identificar compostos que modulam a morte de células de câncer de mama mediadas por células natural killer na presença de um anticorpo terapêutico anti-HER-2.

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Este mês no JoVE edição 198
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