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仔猪围产期窒息模型,用于研究心脏骤停、复苏和自主循环恢复后的心脏损伤和血流动力学
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Article
DOI:
10.3791/64788-v
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10:55 min
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January 13th, 2023
仔猪围产期窒息模型,用于研究心脏骤停、复苏和自主循环恢复后的心脏损伤和血流动力学
January 13th, 2023
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Eydis Oddsdottir Stenersen1,2, Annette Olsen2, Maria Melheim3, Rønnaug Solberg3,4, Ingrid Dannevig5, Georg Schmölzer6,7, Po-Yin Cheung6,7, Britt Nakstad8,9, Ola Didrik Saugstad10,11, Arild Rønnestad1,2, Anne Lee Solevåg2
1Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 2Department of Neonatal Intensive Care, Division of Pediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, 3Department of Pediatric Research, Division of Paediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, 4Department of Pediatrics, Vestfold Hospital Trust, 5Department of Anesthesiology, Oslo University Hospital Rikshospitalet, 6Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, 7Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, 8Division of Paediatric and Adolescent Medicine, Institute of Clinical Medicine, University of Oslo, 9Department of Paediatrics and Adolescent Health, University of Botswana, 10Department of Pediatric Research, Oslo University Hospital, University of Oslo, 11Department of Pediatrics, Robert H Lurie Medical Research Center, Northwestern University Chicago
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Summary
Please note that all translations are automatically generated.
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该仔猪模型包括手术器械、窒息直至心脏骤停、复苏和复苏后观察。该模型允许每只动物进行多次采样,并且通过使用连续侵入性动脉血压、心电图和非侵入性心输出量监测,它提供了围产期窒息和新生儿心肺复苏中的血流动力学和心脏病理生理学知识。