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Ein perinatales Asphyxie-Modell für Ferkel zur Untersuchung von Herzverletzungen und Hämodynamik nach Herzstillstand, Wiederbelebung und der Rückkehr der Spontanzirkulation
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Ein perinatales Asphyxie-Modell für Ferkel zur Untersuchung von Herzverletzungen und Hämodynamik nach Herzstillstand, Wiederbelebung und der Rückkehr der Spontanzirkulation

Article DOI: 10.3791/64788-v • 10:55 min • January 13th, 2023
January 13th, 2023 •
1,2, 2, 3, 3,4, 5, 6,7, 6,7, 8,9, 10,11, 1,2, 2
1Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 2Department of Neonatal Intensive Care, Division of Pediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, 3Department of Pediatric Research, Division of Paediatric and Adolescent Medicine, Oslo University Hospital Rikshospitalet, 4Department of Pediatrics, Vestfold Hospital Trust, 5Department of Anesthesiology, Oslo University Hospital Rikshospitalet, 6Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, 7Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, 8Division of Paediatric and Adolescent Medicine, Institute of Clinical Medicine, University of Oslo, 9Department of Paediatrics and Adolescent Health, University of Botswana, 10Department of Pediatric Research, Oslo University Hospital, University of Oslo, 11Department of Pediatrics, Robert H Lurie Medical Research Center, Northwestern University Chicago

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Dieses Ferkelmodell umfasst chirurgische Instrumente, Erstickung bis zum Herzstillstand, Wiederbelebung und Beobachtung nach der Reanimation. Das Modell ermöglicht eine mehrfache Probenahme pro Tier und bietet durch die kontinuierliche invasive Überwachung des arteriellen Blutdrucks, des EKGs und des nicht-invasiven Herzzeitvolumens Kenntnisse über die Hämodynamik und die Pathophysiologie des Herzens bei perinataler Asphyxie und Herz-Lungen-Wiederbelebung bei Neugeborenen.

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Medizin Heft 191
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