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Journal / Biology / Effizientes PAM-loses Baseneditieren für die…
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Effizientes PAM-loses Baseneditieren für die Zebrafisch-Modellierung menschlicher genetischer Erkrankungen mit zSpRY-ABE8e
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Effizientes PAM-loses Baseneditieren für die Zebrafisch-Modellierung menschlicher genetischer Erkrankungen mit zSpRY-ABE8e

Article DOI: 10.3791/64977-v • 07:31 min • February 17th, 2023
February 17th, 2023 •
1,2, 3, 1,2, 4, 1,2, 1,2
1Key Laboratory of Brain, Cognition and Education Science, Ministry of Education, 2Institute for Brain Research and Rehabilitation, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, 3Institute of Modern Aquaculture Science and Engineering, Guangdong Provincial Engineering Technology Research Center for Environmentally Friendly Aquaculture, Guangdong Provincial Key Laboratory for Healthy and Safe Aquaculture, School of Life Sciences, South China Normal University, 4Department of Pathology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences

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Dieses Protokoll beschreibt, wie eine effiziente Adeninbasen-Editierung ohne PAM-Beschränkung durchgeführt werden kann, um ein präzises Zebrafisch-Krankheitsmodell mit zSpRY-ABE8e zu konstruieren.

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Widerruf Heft 192
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