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JoVE Journal Biology
Intervista
 
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Intervista: HIV-1 DNA provirale escissione Utilizzando un ricombinasi Evolved

Article doi: 10.3791/793
June 16th, 2008 •
1
1Department of Cell Biology and Virology, Heinrich-Pette-Institute for Experimental Virology and Immunology, University of Hamburg

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June 16th, 2008

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Corrente di HIV-1 strategie agire per sopprimere il ciclo di vita virale, ma non in modo efficace sradicare l'infezione. In questo studio dimostriamo che una ricombinasi progettato può DNA in modo efficiente accise integrati di HIV-1 provirale dal genoma delle cellule infette.

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