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Generation of Transgenic C. elegans by Biolistic Transformation
 

Generation of Transgenic C. elegans by Biolistic Transformation

Article DOI: 10.3791/2090
August 23rd, 2010

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Summary August 23rd, 2010

Transgenic worms are commonly used in C. elegans research. Described is a simple, yet effective, protocol to introduce transgenes into worms using biolistic bombardment with DNA-coated gold particles. The effort involved and results of bombardment compare favorably with microinjection for the generation of transgenic animals.

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