Journal
/
Medicine
/
Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

DOI:
10.3791/2737-v

•

06:03 min

•

July 12, 2011

•

, , , , ,
1Conrad Jobst Vascular Research Laboratories, Section of Vascular Surgery,University of Michigan , 2Department of Pharmacology,University of Michigan

Chapters

  • 00:05Title
  • 01:12Procedure to Anesthetize Mice
  • 01:57Mouse Micro-surgery and Recovery
  • 04:16Representative Post-surgical Analyses
  • 05:39Conclusion: Surgical Precaution

Summary

Automatic Translation

Automatic Translation

The electrolytic induction of endothelial activation to the internal surface of the Inferior Vena Cava results in venous type thrombus formation due to endothelial activation and partial blood stasis, two components of Virchow's triad.

Tags

Electrolytic Inferior Vena Cava ModelEIMVenous ThrombosisAnimal ModelsDVT ResearchThrombus FormationThrombus ResolutionTherapeutic CompoundsPotential Therapeutic Antagonist CompoundsThrombosed VeinPartial StasisMajor VeinContinuous Blood FlowTherapeutic AgentsDynamic FashionSensitivityVenous Endothelial Cell ActivationLeukocyte MigrationVenous ThrombogenesisAnalytical Purposes

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

Microsurgical Venous Pouch Arterial-Bifurcation Aneurysms in the Rabbit Model: Technical Aspects

Mouse Complete Stasis Model of Inferior Vena Cava Thrombosis

Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.

Implantation of Inferior Vena Cava Interposition Graft in Mouse Model

Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor Growth.

Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel

Ferric Chloride-induced Murine Thrombosis Models

Patch Angioplasty in the Rat Aorta or Inferior Vena Cava

A Rat Model of Orthotopic Liver Transplantation Using a Novel Magnetic Anastomosis Technique for Suprahepatic Vena Cava Reconstruction

Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury

Read Article