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Chapters
- 00:05Title
- 01:29Preparation for Transplant Surgery
- 03:51Transplantation of Glial Progenitor Cells
- 09:49Representative Results of Glial Cell Transplantation Experiments
- 10:33Conclusion
Neural precursor transplantation is a promising strategy for protecting and/or replacing lost/dysfunctional cervical phrenic motor neurons in spinal cord injury (SCI) and the motor neuron disorder, amyotrophic laterals sclerosis (ALS). We provide a protocol for cell delivery to cervical spinal cord ventral horn in rodent models of ALS and SCI.
Tags
Intraspinal Cell TransplantationTargeting Cervical Ventral HornAmyotrophic Lateral SclerosisTraumatic Spinal Cord InjuryRespiratory CompromisePhrenic Motor Neuron LossMotor Neuron DisorderRapid DegenerationUpper And Lower Motor NeuronsRespiratory ParalysisDiaphragm InnervationFamilial CasesCu/Zn Superoxide Dismutase 1 GeneSOD1 Gene MutationsTransgenic Mice And RatsAnimal ModelsSpinal Cord InjuryHeterogeneous Conditions
