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Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue
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Neuroscience
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JoVE Journal Neuroscience
Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

DOI:
10.3791/50004-v

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10:18 min

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October 29, 2012

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,
1Department of Molecular & Human Genetics,Baylor College of Medicine (BCM), 2Department of Neuroscience,Baylor College of Medicine (BCM), 3Jan and Dan Duncan Neurological Research Institute,Texas Children’s Hospital

Chapters

  • 00:05Title
  • 01:34Assembly of Implant
  • 03:33Assembly of Fiber Optic Coupler Cord
  • 05:32Surgical Implantation
  • 08:40Results: Fiber Optic Implantation
  • 09:45Conclusion

Summary

Automatic Translation

Automatic Translation

The development of optogenetics now provides the means to precisely stimulate genetically defined neurons and circuits, both in vitro and in vivo. Here we describe the assembly and implantation of a fiber optic for chronic photostimulation of brain tissue.

Tags

OptogeneticsFiber-optic ImplantationChronic StimulationNeuronal ConnectivityElectrophysiologyCell-type SpecificIn VivoFiber Optic CouplerPhotostimulationNeuronal Circuits

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