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In vitro Metylering analys för att studera protein Arginin Metylering
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In vitro Metylering analys för att studera protein Arginin Metylering

Article DOI: 10.3791/51997-v • 10:01 min • October 5th, 2014
October 5th, 2014 •
1, 1, 1, 1, 1, 1,2, 1,3
1Department of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, 2Department of Hematology and Oncology, University of Illinois at Chicago, 3Jesse Brown Veterans Affairs Medical Center

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Protein arginin metylering, katalyserad av en klass av enzymer viz. Protein arginin metyl transferaser (PRMTs), är processen av enzymatisk tillsättning av metylgrupp (er) till argininer inom proteiner. In vitro-metylering analysen är den mest pålitliga verktyg för att bedöma metyleringsstatus av kända eller nya PRMT substrat.

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Genetik PRMT protein metylering SAMe arginin denaturerad proteiner metylering analys
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