/
/
Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:05Title
- 01:08Poly(N-isopropylacrylamide)-g-chonodroitin Sulfate Synthesis
- 02:16Calcium-alginate Crosslinked Microparticle Synthesis and Preparation of the Adhesives
- 03:58Bioadhesive Mechanical Tensile Tests
- 06:04Qualitative Cell Viability Using a Live/Dead Assay
- 09:36Results: Evaluation of In Vitro Mechanical and Biological Studies
- 11:02Conclusion
An injectable tissue engineering scaffold composed of poly(N-isopropylacrylamide)-graft-chondroitin sulfate (PNIPAAm-g-CS)-containing alginate microparticles was prepared. The adhesive strength, swelling properties and in vitro biocompatibility are analyzed in this study. The characterization techniques developed here may be applicable to other thermogelling systems.
