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The TreadWheel: Interval Training Protocol for Gently Induced Exercise in Drosophila melanogaster
JoVE Journal
Genetics
This content is Free Access.
JoVE Journal Genetics
The TreadWheel: Interval Training Protocol for Gently Induced Exercise in Drosophila melanogaster
DOI:

07:21 min

June 08, 2018

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Chapters

  • 00:04Title
  • 00:37Fly Collection and Maintenance
  • 03:27Exercise Protocol
  • 05:29Results: Exercise and Diet Effects on Protein-levels and Locomotion
  • 06:51Conclusion

Summary

Automatic Translation

The TreadWheel uses rotational motion to gently induce exercise in adult Drosophila melanogaster by exploiting flies' innate, negative geotaxis. It allows for analysis of the interactions between exercise and factors, such as genotype, sex, and diet, and their effect on physiological and molecular assays to assess metabolic health.

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