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JoVE Journal Bioengineering
Hyaluronsyre basert Hydrogels for 3-dimensjonale kultur pasient-avledede glioblastom celler
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Hyaluronsyre basert Hydrogels for 3-dimensjonale kultur pasient-avledede glioblastom celler

Article DOI: 10.3791/58176-v • 08:35 min • August 24th, 2018
August 24th, 2018 •
1, 1, 1, 2
1Department of Bioengineering, University of California, Los Angeles, 2Department of Bioengineering, Jonsson Comprehensive Cancer Center, Broad Stem Cell Research Center, Brain Research Institute, University of California, Los Angeles

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Her presenterer vi en protokoll for tredimensjonale kultur av pasient-avledede glioblastom celler i ortogonalt tunable biologisk materiale designet for å etterligne brain matrix. Denne tilnærmingen gir en i vitro, eksperimentelle plattform som opprettholder mange egenskaper i vivo glioblastom celler vanligvis mistet i kultur.

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Bioteknologi problemet 138 hyaluronsyre 3D kultur glioblastom microenvironment ekstracellulær matrix biomateriale mechanobiology resistens
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