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Tri-layered Electrospinning to Mimic Native Arterial Architecture using Polycaprolactone, Elastin, and Collagen: A Preliminary Study
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Bioengineering
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JoVE Journal Bioengineering
Tri-layered Electrospinning to Mimic Native Arterial Architecture using Polycaprolactone, Elastin, and Collagen: A Preliminary Study

Tri-layered Electrospinning to Mimic Native Arterial Architecture using Polycaprolactone, Elastin, and Collagen: A Preliminary Study

DOI:
10.3791/2084-v

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10:47 min

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January 04, 2011

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, , , ,
1Department of Biomedical Engineering,Virginia Commonwealth University, 2Department of Anatomy and Neurobiology,Virginia Commonwealth University, 3Department of Cardiovascular Surgery,University Hospital of Geneva

Chapters

  • 00:05Title
  • 00:58Introduction
  • 01:16Electrospinning of Arterial Materials
  • 04:41Evaluation of Electrospun Materials
  • 08:30Exlectrospinning of Native Arterial Architecture
  • 10:11Conclusion

Summary

Automatic Translation

Automatic Translation

The aim of this study was to mimic the native three layered architecture of the arterial wall. To accomplish this, electrospinning was employed with the use of a 3-1 (input-output) nozzle and blends of polycaprolactone, elastin, and collagen.

Tags

Tri-layered ElectrospinningNative Arterial ArchitecturePolycaprolactoneElastinCollagenMechanical PropertiesMulti-layered Electrospun ConduitUniaxial Tensile TestingDynamic ComplianceSuture RetentionBurst StrengthModulus RangeCircumferential Wall StressMathematical Modeling

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