Our group has developed a bioreactor culture system that mimics the physiological pulsatile stresses of the cardiovascular system to regenerate implantable small-diameter vascular grafts.
Huang, A. H., Niklason, L. E. Engineering Biological-Based Vascular Grafts Using a Pulsatile Bioreactor. J. Vis. Exp. (52), e2646, doi:10.3791/2646 (2011).