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Kvantitativ sammenligning af Cis-Regulatory Element (CRE) Aktiviteter i transgene Drosophila melanogaster

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Kvantitativ sammenligning af Cis-Regulatory Element (CRE) Aktiviteter i transgene Drosophila melanogaster
Article DOI: 10.3791/3395 • 08:19 min • December 19th, 2011
December 19th, 2011 •

William A. Rogers¹, Thomas M. Williams²

¹Department of Biology, University of Dayton, ²Department of Biology, Center for Tissue Regeneration and Engineering at Dayton, University of Dayton

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Fænotypiske variation for egenskaber kan skyldes mutationer i cis-regulerende element (CRE) sekvenser, der kontrollerer genekspression mønstre. Metoder afledt til brug i Drosophila melanogaster kan kvantitativt sammenligne niveauet af rumlige og tidsmæssige mønstre af genekspression medieret ved ændret eller naturligt forekommende CRE varianter.

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Developmental Biology Cis-regulerende element CRE cis-regulerende modul forstærker site-specifikke integration reporter transgener konfokal mikroskopi lovgivningsmæssige logik transskriptionsfaktorer bindingssteder,

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Journal (Biology)

Journal (Biology)

Kvantitativ sammenligning af Cis-Regulatory Element (CRE) Aktiviteter i transgene Drosophila melanogaster

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