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Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
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Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

DOI:
10.3791/3852-v

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11:17 min

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October 12, 2012

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, , , ,
1Department of Pharmacology,New York Medical College , 2Department of Anesthesiology,New York Medical College

Chapters

  • 00:00Title
  • 00:05Introduction
  • 02:01Investigators
  • 02:25Assay Apparatus
  • 02:59Degradation by Heparinase
  • 05:08Assay Cartridges
  • 06:21Assay Procedure
  • 09:22Results

Summary

Automatic Translation

Automatic Translation

Demonstration of a rapid quantitative assay of the inhibition of blood coagulation by the low-molecular-weight-heparin, enoxaparin. The contribution of enoxaparin is assessed by removing its influence through digestion with heparinase. A fuller description of the assay is detailed in our published paper.1 The assay still requires clinical confirmation.

Tags

Rapid Point-of-Care AssayEnoxaparinAnticoagulant EfficacyWhole BloodClinical AssayLow-molecular-weight-heparin (LMWH)QuantificationHeparinaseVacutainer TubesBaseline Anticoagulated StatusClotting TimeHemochron 801 ApparatusAssay CartridgesSensitivity

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