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JoVE Journal
Immunology and Infection

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Non-invasive Imaging of Disseminated Candidiasis in Zebrafish Larvae
 
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Non-invasive Imaging of Disseminated Candidiasis in Zebrafish Larvae

Article doi: 10.3791/4051
July 30th, 2012

Summary July 30th, 2012

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The rapid development, small size and transparency of zebrafish are tremendous advantages for the study of innate immune control of infection1-4. Here we demonstrate techniques for infecting zebrafish larvae using the fungal pathogen Candida albicans by microinjection, methodology recently used to implicate phagocyte NADPH oxidase activity in control of fungal dimorphism5.

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