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1Department of Pharmacology,Vanderbilt University, 2Vanderbilt Center for Bone Biology,Vanderbilt University, 3Department of Veterans Affairs,Tennessee Valley Healthcare System (VISN 9), 4Department of Medicine, Division of Clinical Pharmacology,Vanderbilt University, 5Department of Cancer Biology,Vanderbilt University
Chapters
- 00:05Title
- 01:22Cell Maintenance and Preparation
- 02:34Intracardiac Inoculation
- 04:26Intratibial Injection
- 06:57Representative Bone Metastasis Results
- 08:05Conclusion
I modelli animali sono spesso utilizzati per studiare metastasi alle ossa. In questo protocollo si descrivono due metodi comuni di inoculo del tumore per gli studi di metastasi ossee e descrivere brevemente alcune delle analisi utilizzati per monitorare e quantificare questi modelli.
Tags
Bone MetastasisMalignanciesBreast CancerProstate CancerLung CancerMolecular MechanismsTumor GrowthIn Vivo ModelsIntracardiac InoculationAthymic BalbC MicePC-3 Prostate CancerLung CarcinomaMouse Mammary Fat Pad TumorsMDA-MB-231 Breast Cancer ModelGFP ExpressionOsteotropismMetastasis To LungLiverAdrenal GlandsIntratibial InjectionsMammary Fat Pad Injections
