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Cell Death samband med onormal Mitos observerades av Confocal Imaging i Live cancerceller
 

Cell Death samband med onormal Mitos observerades av Confocal Imaging i Live cancerceller

Article doi: 10.3791/50568
August 21st, 2013

Summary August 21st, 2013

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Den cytotoxiska aktiviteten hos fenantridin PJ-34 i cancerceller som genomgår mitos dokumenterades i realtid genom levande konfokal avbildning. PJ-34 utrotas human bröstcancer MDA-MB-231 celler, som hyser extra-centrosomes i mitos. Till skillnad från vanlig bifokala mitos, var extra-centrosomes inte klustrade i de två spindeln poler i närvaro av PJ-34.

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