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Journal / Immunology and Infection / Killer Kunstig antigen-præsenterende celler…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Killer Kunstig antigen-præsenterende celler (KaAPC) til effektiv
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Killer Kunstig antigen-præsenterende celler (KaAPC) til effektiv

Article DOI: 10.3791/51859-v • 08:12 min • August 11th, 2014
August 11th, 2014 •
1, 2,3, 1, 1
1Department of Pathology, Institute of Cell Engineering, Johns Hopkins University, 2Department of Internal Medicine I, University of Regensburg, 3Department of Rheumatology, Asklepios Medical Center

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Retningslinjer præsenteres til generering af killer kunstige antigenpræsenterende celler, KaAPC, et effektivt værktøj til in vitro-udtømning af humane antigen-specifikke T-celler, og en alternativ løsning til cellulær immunterapi til behandling af T-celle-medierede autoimmune sygdomme i et antigen specifik måde uden at kompromittere den resterende immunsystemet.

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Immunologi Autoimmunity apoptose antigenspecifikke CD8 + T-celler HLA-A2-lg Fas / Fas-L KaAPC
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